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RESEARCHLast Updated: May 14, 2026

AlphaFold

DeepMind's protein structure prediction system. Predicts the 3D shape of proteins from amino acid sequences with near-experimental accuracy.

AIght Score84how it's scored →
AIght’s take

“Changed what's tractable. Changed what's interesting. Most things still aren't either.”

— Mankaran, after using it long enough to mean it

Scoring Breakdown

Utility90.0
Privacy75.0
Speed72.0
Cost95.0
Transparency88.0
PricingFree
Risk LevelLow
LicensingOpen Source
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Who it's for

For Builders

Move faster with an AI co-pilot

Offload the repetitive, automate the tedious, and focus on the creative parts of your work that actually need you.

For Learners

Learn by doing, not by watching

Ask it anything, get back an explanation calibrated exactly to your level. The best tutor you've ever had doesn't charge by the hour.

The Assessment

Strengths
  • ✓ Biology
  • ✓ Protein
  • ✓ Research
  • ✓ Open-source
Economics

The pricing reality

The Free Tier

Fully free via EBI web interface

The Cliff

None

Monthly Cost

Free

What AlphaFold replacesYou can probably stop using:
  • ✕weeks of crystallography for an initial structural guess
  • ✕the literature deep-dive for 'has anyone modeled this?'

What AlphaFold can’t do

It predicts the structure. You decide what to ask next.

AlphaFold reshaped what's tractable in structural biology. The taste required to know which prediction is actually meaningful — which protein matters, why, for whom — is still a scientist's job.

Read the essay →